Success Stories
At ENLIGHTEnMENT, our research breakthrough in light chain amyloidosis has been a pivotal moment in our journey. By characterizing the cardiac phenotype of patients with AL-CA, we have made significant strides in understanding this rare disease. Through our dedicated efforts, we aim to create and characterize animal models with features of AL-CA, elucidate cardiotoxicity mechanisms, and investigate potential therapeutic interventions. Our interdisciplinary team, in collaboration with esteemed institutions, is committed to pushing boundaries and making a difference in the field of amyloidosis research.
Award by the European Society of Cardiology Working Group on Cellular Biology of the Heart & Myocardial Function meeting in Napples, Italy, November 2023
Raising awareness
ENLIGHTEnMENT is passionate about raising awareness about amyloidosis through educational programs and community outreach initiatives. By engaging with the public, healthcare professionals, and researchers, we strive to spread knowledge and empower individuals to recognise the signs and symptoms of this disease. Through our educational workshops and campaigns, we aim to make a lasting impact on early diagnosis and successful management of AL-CA. Join us in our mission to drive change and support those affected by amyloidosis.
Meet the team of experts
Dr. Andreadou, PhD, is a Professor of Pharmacology in School of Pharmacy, NKUA and has a long term experience in cardiac toxicity, and cardiac pharmacology in animal models. She is an expert in molecular signaling of the pathophysiology of the heart and the required molecular techniques and can provide excellent guidance for the proposal.
Dr. Kastritis, MD PhD, is a Professor of School of Medicine NKUA, and he is already accredited as an expert in the field of amyloidosis and his group has published numerous publications on the management of AL amyloidosis. His clinical expertise will provide the translational insight, the patient samples and required clinical data for this proposal.
Dr. Papanikolaou, MD, is an expert histopathologist in recognising plasma cell dyscrasias and amyloidosis histology features in human samples and has collaborated with the Department of Clinical Therapeutics in the clinical practice and research projects. Her participation is of utmost importance for the histological evaluation of the proposed animal model.
Dr. Davos, MD, PhD, is a cardiologist and Senior researcher in the Cardiovascular Research Laboratory, BRFFA. His contribution to the evaluation of echocardiographic data and characterization of the cardiac phenotype of the proposed model is highly significant.
Dr. Ribeout is a molecular neurobiologist with an extensive background in applying molecular tools to the study of disease pathogenesis in cellular and in vivo models, including expression and purification of recombinant (cell-produced) proteins, and the application of viral expression approaches. Dr. Rideout’s background and experience is very well suited to help achieve the goals of this project, particularly within the tasks requiring the expression and purification of proteins from mammalian cells.
Dr. Nikolaou, is a Post Doctoral research fellow who has accelerated the establishment of in vivo and in vitro models of light chain associated cardiotoxicity. She is Felasa accredited and has experience in in vivo experimental protocols, so her contribution throughout the project will be valuable.
Dr. Varela, PhD is an expert technician in performing echocardiography evaluation in laboratory animals. She is a highly valuable member of the research team due to her experience, important research work and professionalism.
Supporting Amyloidosis Research
ENLIGHTEnMENT, based in Athens, Greece, is dedicated to providing novel research data and supporting amyloidosis research. Funded by the Hellenic Foundation for Research and Innovation, our team of experts is committed to advancing our understanding of light chain amyloidosis and associated cardiotoxicity. Through collaboration with leading institutions and active involvement in funding initiatives, we aim to make a meaningful impact on the lives of those affected by this rare disease. Contact us today to learn more about our work and how you can support our mission.
Call to Action
Ready to join us in our mission to support amyloidosis research and raise awareness about this rare disease? Get involved today and be a part of our journey towards making a difference. Contact ENLIGHTEnMENT to learn more about how you can contribute to our cause. Together, we can drive change and improve the lives of those affected by amyloidosis.
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